The DNA (DeoxyriboNucleic Acid) carries all the genetic coding for living organisms with the instructions needed for growth, development and functions.
The famous double-spiral (X) is made up of nucleotides, consisting of polymers of sugar linked to phosphate, with one each of four different nitrogen bases (G, T, A and C) attached to the nucleotides. The sequence of the different nucleotides is highly identical within a species, yet thousands of variations at specific points of the genome occur; these are called Single Nucleotide Polymorphism, or more commonly: SNP. SNPs are variations that can explain differences in your appearance, aging and fitness.
Today, thanks to advanced DNA technology we have defined 16 SNPs that have been verified in two independent peer-reviewed publications. These 16 SNPs will measure the key drivers behind your aging and they are following the 5 different types of aging.
Our DNA test has been validated in over 800 samples at an external laboratory using PCR and Sanger sequencing which gave a 100% agreement in test results.
While it has long been recognized that environmental and lifestyle factors play a key role in skin aging, the advance of more reliable DNA research have shown that as much as 60% of aging is dependent on genetic factors.
There are 5 different types of aging that are affected by genetic factors as well as environmental and lifestyle factors.
Like many components of your body, collagen undergoes continuous changes on an ongoing basis throughout your life. When you are younger, your body makes more collagen than it loses; after about the age of 40, collagen loss can accelerate leading to a decline in the health and appearance of your skin (i.e. wrinkles, roughness, sagging along with poor wound healing, acne, rosacea and eczema).
We test 3 SNPs which affect degradation and protection of collagen.
Glycation occurs when excess bodily glucose molecules link to the skin’s collagen and elastin fibers. Glycated fibers can become rigid, less elastic and have reduced regenerative ability, which can lead to damage such as laxity, cracking and thinning skin.
We test 1 SNP which affects the level of glucose which in turn affects glycation.
Sun exposure plays a significant factor in aging of the skin causing a breakdown in the DNA. This leads to skin aging signs such as dryness, loss of elasticity, wrinkles and an uneven skin tone known as pigmentation.
We call this category the ALLÉL® T-Series.
For this we have 5 SNPs that we test that affect skin cell melanin production and repair of UV damage.
We often hear about antioxidants found in fruits and berries, and in food supplements like vitamin C; yet the world’s most powerful antioxidants are present in our own body: Superoxide Dismutase and Glutathione Peroxides. The higher the levels, the less prone we are to the destructive effects of free radicals.
If the body’s own anti-oxidative capacity is overwhelmed, oxidative stress may occur in the skin. This is a leading cause of premature wrinkling, aging and dull skin.
We test 3 SNPs, that protect the skin against oxidative stress.
Inflammation is the skin’s first line of defense against foreign substances like bacteria and chemicals. Excessive inflammation is one of the most common terms in early onset skin aging thereby resulting in a premature aging called ”inflamm-aging”. The signs include skin sensitiveness, redness, itching and irritation; various agents can cause skin irritation including perfume, chemicals and pollution.
We test 5 SNPs which affect the skin’s protection against inflammation.
The Allél Box includes your DNA based serum and cream, cleanser, an eye cream, sun protection as well as your individual vitamins.
THREE MONTHS SUPPLY
During your consultation at Concept-Clinic we will test your DNA and measure the key drivers behind your aging. We will also organize a thorough consultation with our in-house beauty expert who will establish the current state of your skin.
Your DNA report will be ready 2 weeks later together with your DNA based skincare and complete Skincare kit (which includes a foaming cleanser, sun protection and eye cream). We will explain the modalities of usage and continue to be at your disposal for any question you might have.
Should you wish to receive further clarification or to request a consultation
please contact us either by email or by phone at +41 22 54 000 54